What to Expect in Your First 30 Days on Semaglutide or Tirzepatide
Your GLP-1 Weight Loss Journey Begins Here
If you’re starting your weight loss journey with a GLP-1 medication like Semaglutide (Ozempic, Wegovy) or Tirzepatide (Mounjaro, Zepbound), the first 30 days can feel exciting, but also full of questions.
At
Chronos Body Health & Wellness, we support thousands of patients through their GLP-1 weight loss journey with evidence-based care, physician oversight, and customized support. This blog walks you through
what to expect in your first month, so you feel
informed and
empowered every step of the way.
Week 1: Starting the Lowest Dose
Your journey begins with the lowest available dose, carefully prescribed to help your body adjust and reduce the likelihood of side effects. While results vary from person to person, here’s what many patients experience:
You may notice:
- Appetite starts to decrease within a few days
- Feeling full quicker or less interested in food
- Mild side effects such as nausea, fatigue, constipation, or slight bloating.
Chronos Tip: Hydration and protein-rich, balanced meals can help ease symptoms and
support your early progress.
Week 2: Appetite Shift Becomes Clearer
As you continue on your GLP-1, you may begin to feel more in control around food. This is a major breakthrough for many patients who’ve struggled with:
- Constant hunger
- Emotional or stress eating
- Late-night snacking or sugar cravings
This is also when
modest weight loss (often 2–5 lbs) may begin to appear on the scale, depending on your body type, movement, and eating habits.
"I'm shocked I'm eating so much less and not even missing it." — Chronos patient, Week 2
Week 3: More Energy, Fewer Cravings
By Week 3, many patients report:
- Improved focus and energy
- Steadier blood sugar
and fewer crashes
- Feeling more confident about their ability to make food choices
- 5–10 lbs lost, depending on the individual
This is also the time we encourage you to build supportive routines
around your progress. At Chronos, we offer
personalized fitness programs
and
nutrition coaching to help you sustain and amplify your results.
Week 4: Momentum Builds
By the end of your first month on Semaglutide or Tirzepatide, you’ve likely experienced:
- 5–15+ lbs of weight loss
(depending on your starting point)
- A major shift in your hunger patterns and
portion sizes
- Improved relationship with food
This is where confidence grows, and where some patients explore complementary treatments like:
- Body contouring (CoolSculpting® Elite) for stubborn fat areas
- Skin tightening or
facial rejuvenation
- Ongoing weight and lifestyle support through nutrition or hormone optimization
The Chronos Difference
Starting a GLP-1 medication is a big decision, and one you shouldn’t make alone. At Chronos, we go far beyond a prescription pad. Our physician-led weight loss program is designed to help you stay safe, supported, and successful.
When you start Semaglutide or Tirzepatide at Chronos, you get:
- Ongoing provider oversight with our accredited team (All follow-up care included. Only pay for medication packages)
- Transparent pricing and clear dose escalation (No hidden fees or memberships)
- Support for side effects or questions at any stage
- Nutritional guidance and tips
- A
compassionate team that will guide you to success
Your First 30 Days Matter. Let’s Do It Right!
Whether you're just curious or ready to begin, our team is here to help you start strong. The first month on Semaglutide or Tirzepatide can be life-changing, and at Chronos, you’ll never do it alone.
Schedule your consultation today to speak with our medical team and find out if GLP-1 therapy is right for you.
